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Mafatm1.1(cre)Cbm
Targeted Allele Detail
Summary
Symbol: Mafatm1.1(cre)Cbm
Name: MAF bZIP transcription factor A; targeted mutation 1.1, Carmen Birchmeier
MGI ID: MGI:5806113
Synonyms: Mafa-cre
Gene: Mafa  Location: Chr15:75617339-75620077 bp, - strand  Genetic Position: Chr15, 34.82 cM
Alliance: Mafatm1.1(cre)Cbm page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:236516
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutations:    Insertion, Intragenic deletion
 
Mafatm1.1(cre)Cbm expression driven by 1 gene
 
Mutation details: The allele was generated by homologous recombination in embryonic stem (ES) cells. The mouse Mafa coding region was replaced by a cassette containing the cre recombinase open reading frame followed by a FRT flanked neomycin resistance cassette. The neomycin cassette was removed by crossing F1 mice with FLPe deleter mice. (J:253253)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Mafa (mouse)
Summary of all recombinase alleles driven by Mafa.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mafa Mutation:  20 strains or lines available
References
Original:  J:236516 Birchmeier C, Submission for a Mafa-cre. MGI Direct Data Submission. 2016;
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory