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Sik3em3Iiis
Endonuclease-mediated Allele Detail
Summary
Symbol: Sik3em3Iiis
Name: SIK family kinase 3; endonuclease-mediated mutation 3, Masashi Yanagisawa and Hiromasa Funato
MGI ID: MGI:5806545
Synonyms: Flag-SIK3 (SLP), Sik3em3Staka, Sik3Flag,Slp
Gene: Sik3  Location: Chr9:45924118-46135492 bp, + strand  Genetic Position: Chr9, 25.36 cM
Alliance: Sik3em3Iiis page
Mutation
origin
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Endonuclease-mediated (Not Specified)
Mutation:    Insertion
 
Mutation details: CRISPR/Cas technology inserted a Flag-haemagglutinin (HA)-coding sequence immediately after the second methionine in zygotes carrying the Sik3Slp mutation (an exon 13 skingging G to A point mutation in intron 13). (J:236598)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Sik3 Mutation:  72 strains or lines available
References
Original:  J:236598 Funato H, et al., Forward-genetics analysis of sleep in randomly mutagenized mice. Nature. 2016 Nov 17;539(7629):378-383
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory