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Adcy1tm2(EGFP/cre/ERT2)Wtsi
Targeted Allele Detail
Summary
Symbol: Adcy1tm2(EGFP/cre/ERT2)Wtsi
Name: adenylate cyclase 1; targeted mutation 2, Wellcome Trust Sanger Institute
MGI ID: MGI:5811651
Gene: Adcy1  Location: Chr11:7013489-7128506 bp, + strand  Genetic Position: Chr11, 4.72 cM, cytoband A2
Alliance: Adcy1tm2(EGFP/cre/ERT2)Wtsi page
Mutation
origin
Mutant Cell Line:  CEPD0106_1_B06
Germline Transmission:  Earliest citation of germline transmission: J:204812
Parent Cell Line:  JM8A3.N1 (ES Cell)
Strain of Origin:  C57BL/6N-Atm1Brd
Project Collection: EUCOMMTOOLS
Mutation
description
Allele Type:    Targeted (Inducible, Recombinase, Reporter)
Inducer:    tamoxifen
Mutation:    Insertion
 
Adcy1tm2(EGFP/cre/ERT2)Wtsi expression driven by 1 gene
 
Mutation detailsAccording to the allele molecular image presented by the International Knockout Mouse Consortium, this allele has one FRT site, an engrailed 2 splice acceptor sequence, an EGFP and cre/ERT2 expression cassette, and a neomycin resistance cassette inserted into intron 3' of exon 3. A single loxP site is inserted between exons 3 and 4. (J:155845)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Adcy1 (mouse)
Summary of all recombinase alleles driven by Adcy1.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Adcy1 Mutation:  73 strains or lines available
References
Original:  J:155845 Wellcome Trust Sanger Institute, Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute. MGI Direct Data Submission. 2010;
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory