Gfaptm2(EGFP/cre/ERT2)Wtsi
Targeted Allele Detail
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| Symbol: |
Gfaptm2(EGFP/cre/ERT2)Wtsi |
| Name: |
glial fibrillary acidic protein; targeted mutation 1, Wellcome Trust Sanger Institute |
| MGI ID: |
MGI:5811821 |
| Gene: |
Gfap Location: Chr11:102778162-102791368 bp, - strand Genetic Position: Chr11, 66.48 cM, cytoband D
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| Alliance: |
Gfaptm2(EGFP/cre/ERT2)Wtsi page
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| Mutant Cell Line: |
CEPD0084_4_A09 |
| Germline Transmission: |
Earliest citation of germline transmission:
J:204812
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| Parent Cell Line: |
JM8.N4 (ES Cell)
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| Strain of Origin: |
C57BL/6N
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| Project Collection: |
EUCOMMTOOLS
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| Allele Type: |
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Targeted (Inducible, Recombinase, Reporter) |
| Inducer: |
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tamoxifen |
| Mutation: |
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Insertion
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Gfaptm2(EGFP/cre/ERT2)Wtsi expression driven by
1 gene
Knock-in expression driven by:
| Organism |
Driver Gene |
Note |
| mouse |
Gfap (MGI:95697) |
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Mutation details: According to the allele molecular image presented by the International Knockout Mouse Consortium, this allele has one FRT site, an engrailed 2 splice acceptor sequence, an EGFP and cre/ERT2 expression cassette, and a neomycin resistance cassette inserted between exons 1 and 2. A single loxP site is inserted between exons 4 and 5.
(J:155845)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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Gfap
(mouse)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Gfap Mutation: |
48 strains or lines available
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| Original: |
J:155645 de la Puente B, et al., Sigma-1 receptors regulate activity-induced spinal sensitization and neuropathic pain after peripheral nerve injury. Pain. 2009 Oct;145(3):294-303 |
| All: |
3 reference(s) |
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Analysis Tools
