Tg(Npas1-icre,-tdTomato)1Cschn
Transgene Detail
|
|
| Symbol: |
Tg(Npas1-icre,-tdTomato)1Cschn |
| Name: |
transgene insertion 1, C Savio Chan |
| MGI ID: |
MGI:5816528 |
| Synonyms: |
Npas1Cre-2A-tdTomato, Npas1- Cre-2A-tdTomato, Npas1- Cre-2A-tdTomato BAC transgenic line 1, Npas1-tdTom |
| Transgene: |
Tg(Npas1-icre,-tdTomato)1Cschn Location: unknown
|
| Alliance: |
Tg(Npas1-icre,-tdTomato)1Cschn page
|
|
|
|
| Transgene Type: |
|
Transgenic (Recombinase, Reporter) |
| Mutation: |
|
Insertion
|
| |
|
Tg(Npas1-icre,-tdTomato)1Cschn expression driven by
1 gene
Transgene expression driven by:
| Organism |
Driver Gene |
Note |
| mouse |
Npas1 (MGI:109205) |
|
|
| |
|
Mutation details: A mouse bacterial artificial chromosome (BAC) containing the entire Npas1 gene, was modified by inserting iCre-2A (cleavable fusion peptide sequence)-tdTomato and polyadenylation sequence from bovine growth hormone downstream of the ATG translation initiation codon, and removing Npas1 coding sequence. A transgenic insert made from this modified BAC was microinjected into the pronucleus of C57BL/6 fertilized eggs. The resulting Npas1-tdTom transgenic mice from founder line 1 were subsequently maintained on the C57BL/6J background.
(J:237688)
|
|
|
|
Activity: |
 Tissue activity of this recombinase allele
|
|
Driver:
|
Npas1
(mouse)
|
| |
|
|
| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
|
|
| Original: |
J:237688 Hernandez VM, et al., Parvalbumin+ Neurons and Npas1+ Neurons Are Distinct Neuron Classes in the Mouse External Globus Pallidus. J Neurosci. 2015 Aug 26;35(34):11830-47 |
| All: |
11 reference(s) |
|
Analysis Tools
