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Ift80tm1.1Syy
Targeted Allele Detail
Summary
Symbol: Ift80tm1.1Syy
Name: intraflagellar transport 80; targeted mutation 1.1, Shuying Yang
MGI ID: MGI:5818514
Synonyms: IFT80f
Gene: Ift80  Location: Chr3:68799832-68911892 bp, - strand  Genetic Position: Chr3, 32.07 cM, cytoband E2
Alliance: Ift80tm1.1Syy page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:237888
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6N
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsExon 6 was flanked with loxP sites and an FRT site flanked marker and selection double cassette was inserted into intron 5. The double cassette consists of a beta galactosidase (LacZ) gene cassette and a neomycin resistance gene cassette, separated by a loxP site. The marker-selection cassette was deleted through flp-mediated recombination, leaving a conditional ready allele with a floxed exon 6. (J:236749, J:237888)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ift80 Mutation:  56 strains or lines available
References
Original:  J:237888 Yuan X, et al., Deletion of IFT80 Impairs Epiphyseal and Articular Cartilage Formation Due to Disruption of Chondrocyte Differentiation. PLoS One. 2015;10(6):e0130618
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory