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Foxg1tm1.1(cre)Ddmo
Targeted Allele Detail
Summary
Symbol: Foxg1tm1.1(cre)Ddmo
Name: forkhead box G1; targeted mutation 1.1, Dennis D M O'Leary
MGI ID: MGI:5818697
Synonyms: Foxg1-IRES-Cre
Gene: Foxg1  Location: Chr12:49429666-49433650 bp, + strand  Genetic Position: Chr12, 21.78 cM
Alliance: Foxg1tm1.1(cre)Ddmo page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:231606
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129T/Sv
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
Foxg1tm1.1(cre)Ddmo expression driven by 1 gene
 
Mutation details: An IRES-cre gene followed by an frt-flanked PGK-neo was inserted at 27bp downstream of the stop codon of the gene by homologous recombination in ES cells. Resulting mice were crossed with FLPe expressing mice to remove the PGK-neo cassette. (J:231606)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Foxg1 (mouse)
Summary of all recombinase alleles driven by Foxg1.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Foxg1 Mutation:  29 strains or lines available
References
Original:  J:231606 Kawaguchi D, et al., Generation and analysis of an improved Foxg1-IRES-Cre driver mouse line. Dev Biol. 2016 Apr 1;412(1):139-47
All:  18 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory