About   Help   FAQ
Pax9em1(cre/ERT2)Ychai
Endonuclease-mediated Allele Detail
Summary
Symbol: Pax9em1(cre/ERT2)Ychai
Name: paired box 9; endonuclease-mediated mutation 1, Yang Chai
MGI ID: MGI:5824734
Synonyms: Pax9-CreER
Gene: Pax9  Location: Chr12:56738552-56759607 bp, + strand  Genetic Position: Chr12, 24.53 cM
Alliance: Pax9em1(cre/ERT2)Ychai page
Mutation
origin
Strain of Origin:  (C57BL/6 x DBA)F1
Mutation
description
Allele Type:    Endonuclease-mediated (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Pax9em1(cre/ERT2)Ychai expression driven by 1 gene
 
Mutation details: Plasmids encoding a signal guide RNA designed to introduce an E2A peptide cleavage site-cre/ERT2 into the last exon of the Pax9 gene (immediately before the stop codon) and the cas9 nuclease were introduced into the cytoplasm B6D2F1-derived fertilized eggs with well-recognized pronuclei. (J:236319)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Pax9 (mouse)
Summary of all recombinase alleles driven by Pax9.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pax9 Mutation:  17 strains or lines available
References
Original:  J:236319 Feng J, et al., Generation and characterization of tamoxifen-inducible Pax9-CreER knock-in mice using CrispR/Cas9. Genesis. 2016 Sep;54(9):490-6
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory