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Pax9em1(cre/ERT2)Ychai
Endonuclease-mediated Allele Detail
Summary
Symbol: Pax9em1(cre/ERT2)Ychai
Name: paired box 9; endonuclease-mediated mutation 1, Yang Chai
MGI ID: MGI:5824734
Synonyms: Pax9-CreER
Gene: Pax9  Location: Chr12:56738552-56759607 bp, + strand  Genetic Position: Chr12, 24.53 cM
Alliance: Pax9em1(cre/ERT2)Ychai page
Mutation
origin
Strain of Origin:  (C57BL/6 x DBA)F1
Mutation
description
Allele Type:    Endonuclease-mediated (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Pax9em1(cre/ERT2)Ychai expression driven by 1 gene
 
Mutation details: Plasmids encoding a signal guide RNA designed to introduce an E2A peptide cleavage site-cre/ERT2 into the last exon of the Pax9 gene (immediately before the stop codon) and the cas9 nuclease were introduced into the cytoplasm B6D2F1-derived fertilized eggs with well-recognized pronuclei. (J:236319)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Pax9 (mouse)
Summary of all recombinase alleles driven by Pax9.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pax9 Mutation:  17 strains or lines available
References
Original:  J:236319 Feng J, et al., Generation and characterization of tamoxifen-inducible Pax9-CreER knock-in mice using CrispR/Cas9. Genesis. 2016 Sep;54(9):490-6
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
08/02/2024
MGI 6.24 		The Jackson Laboratory