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Trp63tm2.1Msen
Targeted Allele Detail
Summary
Symbol: Trp63tm2.1Msen
Name: transformation related protein 63; targeted mutation 2.1, Makoto Senoo
MGI ID: MGI:5882555
Gene: Trp63  Location: Chr16:25502513-25710842 bp, + strand  Genetic Position: Chr16, 17.37 cM
Alliance: Trp63tm2.1Msen page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:238904
Parent Cell Line:  v6.5 (ES Cell)
Strain of Origin:  (C57BL/6 x 129S4/SvJae)F1
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation details: A GFP reporter gene and floxed neomycin resistance cassette replaced exons 6 and 7. Cre-mediated recombination removed the selection cassette. (J:238904)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Trp63 Mutation:  60 strains or lines available
References
Original:  J:238904 Suzuki D, et al., The carboxy-terminus of p63 links cell cycle control and the proliferative potential of epidermal progenitor cells. Development. 2015 Jan 15;142(2):282-90
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory