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Gene Expression Data
Assay Details
Assay
Reference: J:121792 Mizuta K, et al., Molecular characterization of GDD1/TMEM16E, the gene product responsible for autosomal dominant gnathodiaphyseal dysplasia. Biochem Biophys Res Commun. 2007 May 25;357(1):126-32
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5883259
Gene symbol: Ano5
Gene name: anoctamin 5
Results
Specimen 3A GDD1: postnatal adult (more )
Structure Level Pattern Image Note
TS28: cardiac muscle tissue Present Regionally restricted 3A GDD1 Expression confined to myofibers; appears to be associated with both cytoplasmic and subsarcolemmal vesicle-like structures.

Specimen 3B GDD1: postnatal adult (more )
Structure Level Pattern Image Note
TS28: femur Present Regionally restricted 3B GDD1 Expression in femoral head cartilage, exclusively in the epiphyseal growth plate.
TS28: long bone epiphyseal plate Present Regionally restricted 3B GDD1 Expression in femoral head cartilage, exclusively in the epiphyseal growth plate.

Specimen 3C GDD1: postnatal adult (more )
Structure Level Pattern Image Note
TS28: long bone epiphyseal plate hypertrophic zone Present Regionally restricted 3C GDD1 Expression in hypertrophic chondrocytes.
TS28: bone Present Regionally restricted 3C GDD1 Expression in osteoblasts lining the trabecular bones.

Specimen 3D GDD1 (left): postnatal adult (more )
Structure Level Pattern Image Note
TS28: bone Present Regionally restricted 3D GDD1 (left panel) Expression in osteoblasts lining the bone surfaces. Expression in endosteal and periosteal osteoblasts.

Specimen 3D GDD1 (right): postnatal adult (more )
Structure Level Pattern Image Note
TS28: cartilaginous joint Present Regionally restricted 3D GDD1 (right panel) Expression in articular cartilage cells.

Specimen E14.5 not shown: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: limb cartilage condensation Weak Authors report weak but significant protein expression in limb bones of E14.5 embryos.

Specimen 3E GDD1: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: tibia Present Regionally restricted 3E GDD1

Specimen E18.5 not shown: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: femur Present Regionally restricted Expression in growth plates of proximal tibia and distal femur.
TS26: tibia Present Regionally restricted Expression in growth plates of proximal tibia and distal femur.

Specimen S4 GDD1: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: tibia Present Regionally restricted S4_GDD1 Expression in distal growth plate of tibia, mainly in prehypertrophic zone chondrocytes. Weaker expression in resting zone chondrocytes.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
09/17/2024
MGI 6.24
The Jackson Laboratory