Rprd1bTg(CAG-cre/Esr1*)32Ichi
Transgenic Allele Detail
|
Symbol: |
Rprd1bTg(CAG-cre/Esr1*)32Ichi |
Name: |
regulation of nuclear pre-mRNA domain containing 1B; transgene insertion 32, Hirotake Ichise |
MGI ID: |
MGI:5888987 |
Synonyms: |
Rprd1bC32delta |
Gene: |
Rprd1b Location: Chr2:157870395-157920127 bp, + strand Genetic Position: Chr2, 78.72 cM, cytoband H2
|
Alliance: |
Rprd1bTg(CAG-cre/Esr1*)32Ichi page
|
|
Germline Transmission: |
Earliest citation of germline transmission:
J:240153
|
Parent Cell Line: |
E14.1 (ES Cell)
|
Strain of Origin: |
129P2/OlaHsd
|
|
Transgene Type: |
|
Transgenic (Inducible, Recombinase) |
Inducer: |
|
tamoxifen |
Mutation: |
|
Insertion
|
|
|
Rprd1bTg(CAG-cre/Esr1*)32Ichi expression driven by
1 gene
Transgene expression driven by:
Organism |
Driver Gene |
Note |
chicken |
CAG |
|
|
|
|
Mutation details: The transgene construct consisting of truncated CAG promoter followed by CreMer fusion protein and truncated Pgk poly-A was inserted into the intorn 3 of Rprd1b gene. Rprd1b is created by FLP-mediated excision of GFP/neo fusion gene from the conditional transgene Rprd1b. After FLP-mediated excision, tissue-specific expression of inducible cre is detected.
(J:240153)
|
|
|
Activity: |
Tissue activity of this recombinase allele
|
Driver:
|
CAG
(chicken)
|
|
|
|
Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
|
Carrying any Rprd1b Mutation: |
16 strains or lines available
|
|
Original: |
J:240153 Ichise H, et al., Establishment of a tamoxifen-inducible Cre-driver mouse strain for widespread and temporal genetic modification in adult mice. Exp Anim. 2016 Jul 29;65(3):231-44 |
All: |
1 reference(s) |
|