Jarid2tm1d(KOMP)Wtsi
Targeted Allele Detail
|
|
| Symbol: |
Jarid2tm1d(KOMP)Wtsi |
| Name: |
jumonji and AT-rich interaction domain containing 2; targeted mutation 1d, Wellcome Trust Sanger Institute |
| MGI ID: |
MGI:5888989 |
| Synonyms: |
Jarid2ko |
| Gene: |
Jarid2 Location: Chr13:44882950-45075119 bp, + strand Genetic Position: Chr13, 21.66 cM
|
| Alliance: |
Jarid2tm1d(KOMP)Wtsi page
|
| IMPC: |
Jarid2 gene page |
|
| Germline Transmission: |
Earliest citation of germline transmission:
J:240642
|
| Parent Cell Line: |
JM8 (ES Cell)
|
| Strain of Origin: |
C57BL/6N
|
| Project Collection: |
KOMP-CSD
|
|
| Allele Type: |
|
Targeted (Null/knockout) |
| Mutation: |
|
Intragenic deletion
|
| |
|
Mutation details: The L1L2_gt0 cassette was inserted at position 44976315 of Chromosome 13 upstream of the critical exon(s) (Build GRCm39). The cassette is composed of an FRT flanked lacZ/neomycin sequence followed by a loxP site. An additional loxP site is inserted downstream of the targeted exon(s) at position 44977253. The critical exon(s) is/are thus flanked by loxP sites. A null/knockout allele was created by flp and cre recombinase expression in mice carrying this allele to remove the lacZ sequence, neo selection cassette and the loxP-flanked critical exon(s).
(J:240642)
|
|
|
| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
|
| Carrying any Jarid2 Mutation: |
375 strains or lines available
|
|
| Original: |
J:240642 Cooper S, et al., Jarid2 binds mono-ubiquitylated H2A lysine 119 to mediate crosstalk between Polycomb complexes PRC1 and PRC2. Nat Commun. 2016 Nov 28;7:13661 |
| All: |
1 reference(s) |
|
Analysis Tools
