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Brs3tm1.1(cre/GFP)Rpa
Targeted Allele Detail
Summary
Symbol: Brs3tm1.1(cre/GFP)Rpa
Name: bombesin-like receptor 3; targeted mutation 1.1, Richard D Palmiter
MGI ID: MGI:5896306
Synonyms: BRS3-IRES-Cre
Gene: Brs3  Location: ChrX:56088434-56094118 bp, + strand  Genetic Position: ChrX, 30.78 cM, cytoband A7.1-A7.2
Alliance: Brs3tm1.1(cre/GFP)Rpa page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:308449
Parent Cell Line:  G4 (ES Cell)
Strain of Origin:  (129S6/SvEvTac x C57BL/6NCrl)F1
Mutation
description
Allele Type:    Targeted (Recombinase, Reporter)
Mutation:    Insertion
 
Brs3tm1.1(cre/GFP)Rpa expression driven by 1 gene
 
Mutation details: IRES-Myc tag-nuclear localization signal (NLS)-cre-GFP-frt-neomycin-frt were introduced just after the termination codon of the X-linked mouse Brs3 gene via homologous recombination. The neomycin cassette was excised through crosses with animals broadly expressing Flp recombinase. (J:101977, J:308449)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Brs3 (mouse)
Summary of all recombinase alleles driven by Brs3.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Brs3 Mutation:  14 strains or lines available
References
Original:  J:308449 Mogul AS, et al., Cre recombinase driver mice reveal lineage-dependent and -independent expression of Brs3 in the mouse brain. eNeuro. 2021 Jul 29;:ENEURO.0252-21.2021
All:  3 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory