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Npy1rtm1(cre/GFP)Rpa
Targeted Allele Detail
Summary
Symbol: Npy1rtm1(cre/GFP)Rpa
Name: neuropeptide Y receptor Y1; targeted mutation 1.1, Richard D Palmiter
MGI ID: MGI:5896318
Gene: Npy1r  Location: Chr8:67149844-67159444 bp, + strand  Genetic Position: Chr8, 33.15 cM, cytoband B3-C2
Alliance: Npy1rtm1(cre/GFP)Rpa page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:234810
Parent Cell Line:  G4 (ES Cell)
Strain of Origin:  (129S6/SvEvTac x C57BL/6NCrl)F1
Mutation
description
Allele Type:    Targeted (Recombinase, Reporter)
Mutation:    Insertion
 
Npy1rtm1(cre/GFP)Rpa expression driven by 1 gene
 
Mutation details: IRES-Myc tag-nuclear localization signal (NLS)-cre-GFP-frt-neomycin-frt were introduced just before the initiation codon of the mouse Npy1r gene via homologous recombination. The frt-flanked neomycin cassette is retained, but cre recombinase is still expressed. (J:234810)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Npy1r (mouse)
Summary of all recombinase alleles driven by Npy1r.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Npy1r Mutation:  25 strains or lines available
References
Original:  J:234810 Padilla SL, et al., Agouti-related peptide neural circuits mediate adaptive behaviors in the starved state. Nat Neurosci. 2016 May;19(5):734-41
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory