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Satb2tm1.1(cre/GFP)Rpa
Targeted Allele Detail
Summary
Symbol: Satb2tm1.1(cre/GFP)Rpa
Name: special AT-rich sequence binding protein 2; targeted mutation 1.1, Richard D Palmiter
MGI ID: MGI:5896327
Synonyms: Satb2Cre
Gene: Satb2  Location: Chr1:56833140-57017809 bp, - strand  Genetic Position: Chr1, 28.72 cM
Alliance: Satb2tm1.1(cre/GFP)Rpa page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:301067
Parent Cell Line:  G4 (ES Cell)
Strain of Origin:  (129S6/SvEvTac x C57BL/6NCrl)F1
Mutation
description
Allele Type:    Targeted (Recombinase, Reporter)
Mutation:    Insertion
 
Satb2tm1.1(cre/GFP)Rpa expression driven by 1 gene
 
Mutation details: IRES-Myc tag-nuclear localization signal (NLS)-cre-GFP-frt-neomycin-frt were introduced just after the termination codon of the mouse Statb2 gene via homologous recombination. The neomycin cassette was excised through crosses with animals broadly expressing Flp recombinase. (J:101977, J:301067)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Satb2 (mouse)
Summary of all recombinase alleles driven by Satb2.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Satb2 Mutation:  43 strains or lines available
References
Original:  J:301067 Jarvie BC, et al., Satb2 neurons in the parabrachial nucleus mediate taste perception. Nat Commun. 2021 Jan 11;12(1):224
All:  4 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory