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Cdh4tm1(cre/ERT2)Jrs
Targeted Allele Detail
Summary
Symbol: Cdh4tm1(cre/ERT2)Jrs
Name: cadherin 4; targeted mutation 1, Joshua R Sanes
MGI ID: MGI:5896331
Synonyms: Cdh4CreER
Gene: Cdh4  Location: Chr2:179084228-179541166 bp, + strand  Genetic Position: Chr2, 101.86 cM
Alliance: Cdh4tm1(cre/ERT2)Jrs page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:235958
Parent Cell Line:  v6.5 (ES Cell)
Strain of Origin:  (C57BL/6 x 129S4/SvJae)F1
Mutation
description
Allele Type:    Targeted (Inducible, Recombinase)
Inducer:    tamoxifen
Mutations:    Insertion, Intragenic deletion
 
Cdh4tm1(cre/ERT2)Jrs expression driven by 1 gene
 
Mutation details: The targeting vector consisting of a FRT flanked neo cassette, a 6xmyc-tagged CreER-T2, and poly-adenylation signal replaced N-term 19 amino acid at the translational start site of the mouse Cdh4 via homologous recombination. (J:235958)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Cdh4 (mouse)
Summary of all recombinase alleles driven by Cdh4.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cdh4 Mutation:  56 strains or lines available
References
Original:  J:235958 Rousso DL, et al., Two Pairs of ON and OFF Retinal Ganglion Cells Are Defined by Intersectional Patterns of Transcription Factor Expression. Cell Rep. 2016 May 31;15(9):1930-44
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory