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Gene Expression Data
Assay Details
Assay
Reference: J:57947 Cachon-Gonzalez MB, et al., The hairless gene of the mouse: relationship of phenotypic effects with expression profile and genotype. Dev Dyn. 1999 Oct;216(2):113-26
Assay type: RNA in situ
MGI Accession ID: MGI:5896429
Gene symbol: Hr
Gene name: lysine demethylase and nuclear receptor corepressor
Probe: hairless probe
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 5a/b: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: rib pre-cartilage condensation Strong 5a/b
TS20: perichondrium Absent 5a/b

Specimen 5c/d: embryonic day 19.5 (more )
Structure Level Pattern Image Note
TS26: rib Present Regionally restricted 5c/d Absent in the dorsal area. Expressed in the ventral parts that join the sternebrae.

Specimen 5e/f: embryonic day 19.5 (more )
Structure Level Pattern Image Note
TS26: rib Present Regionally restricted 5e/f Absent in the bone area. Expressed in the part of the clavicle that articulates with the manubrium.

Specimen 6a/b: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: dental placode Present Regionally restricted 6a/b Expressed in the thickening of the dental lamina.
TS20: oral epithelium Present 6a/b
TS20: oral region mesenchyme Absent 6a/b No expression the mesenchyme of the future mandible body.

Specimen 6c/d: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: enamel organ Present Regionally restricted 6c/d Expressed in the outer and inner enamel epitheliums and the stellate reticulum. Stronger expression in the epitheliums, particularly in the inner epithelium.
TS26: oral epithelium Present 6c/d
TS26: outer enamel epithelium Present 6c/d
TS26: stellate reticulum Present 6c/d
TS26: jaw bone Absent 6c/d
TS26: inner enamel epithelium Present 6c/d Stronger expression.

Specimen 6e/f: embryonic day 19.5 (more )
Structure Level Pattern Image Note
TS26: lip Present Regionally restricted 6e/f Expressed in the lip furrow.
TS26: enamel organ Present Regionally restricted 6e/f Expressed in the outer and inner enamel epitheliums and the stellate reticulum. Stronger expression in the epitheliums, particularly in the inner epithelium.
TS26: oral epithelium Strong 6e/f
TS26: tongue epithelium Strong 6e/f
TS26: jaw bone Absent 6e/f
TS26: outer enamel epithelium Present 6e/f
TS26: stellate reticulum Present 6e/f
TS26: inner enamel epithelium Present 6e/f Stronger expression.

Specimen 6h: embryonic day 19.5 (more )
Structure Level Pattern Image Note
TS26: tongue epithelium Present 6h The hybridisation signal can be seen as black dots.
TS26: inner enamel epithelium Present 6h The hybridisation signal can be seen the strongest over the inner enamel epithelium as black dots.

Specimen 7a/b: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: epidermis Weak 7a/b
TS20: vibrissa follicle Strong 7a/b

Specimen 7c/d: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: hair follicle Strong 7c/d
TS26: vibrissa follicle Strong 7c/d
TS26: hair bulb Strong 7c/d
TS26: hair epidermal placode Strong 7c/d
TS26: hair inner root sheath Strong 7c/d
TS26: hair outer root sheath Strong 7c/d

Specimen 7e/f: embryonic day 19.5 (more )
Structure Level Pattern Image Note
TS26: hair bulb Strong 7e/f
TS26: hair epidermal placode Strong 7e/f
TS26: hair follicle Strong 7e/f
TS26: hair inner root sheath Strong 7e/f
TS26: hair outer root sheath Strong 7e/f

Specimen 7g/h: embryonic day 19.5 (more )
Structure Level Pattern Image Note
TS26: hair bulb Strong 7g/h
TS26: hair epidermal placode Strong 7g/h
TS26: hair follicle Strong 7g/h
TS26: hair inner root sheath Strong 7g/h
TS26: hair outer root sheath Strong 7g/h

Specimen 8a/b: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: optic stalk Present 8a/b
TS24: retina Present 8a/b

Specimen 8c/d: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: inner ear Present 8c/d

Specimen 8e/f: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: colon epithelium Strong 8e/f

Specimen not shown: embryonic day 7.5 (more )
Structure Level Pattern Image Note
TS11: embryo Absent

Specimen not shown: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: embryo Absent

Specimen not shown: embryonic day 12.5 (more )
Note: Summarized in Table 1.
Structure Level Pattern Image Note
TS20: dermis Absent
TS20: heart Absent
TS20: liver Absent
TS20: metanephros Absent
TS20: testis Absent
TS20: nasal cavity epithelium Present
TS20: oral epithelium Present
TS20: oral region gland Present Regionally restricted Expressed in submandibular gland.
TS20: cartilage condensation Strong Expressed in cartilage primordium of future bones such as dorsal ribs, Meckels cartilage, humerus, and scapula, which originate from very different cell groups.
TS20: brain Present Strongest in the cortex.

Specimen not shown: embryonic day 16.5 (more )
Note: Summarized in Table 1.
Structure Level Pattern Image Note
TS24: Meckel's cartilage Absent
TS24: dental papilla Absent
TS24: dermis Absent
TS24: heart Absent
TS24: liver Absent
TS24: metanephros Absent
TS24: testis Absent
TS24: cartilage condensation Strong
TS24: nasal cavity epithelium Strong
TS24: oral epithelium Strong
TS24: rectum epithelium Strong
TS24: tibia Strong
TS24: tongue epithelium Strong
TS24: urethra epithelium Strong
TS24: vibrissa follicle Strong
TS24: inner enamel epithelium Present
TS24: outer enamel epithelium Present
TS24: stellate reticulum Present
TS24: epidermis Present Regionally restricted Expressed in the nares and on the eyelids.
TS24: hair follicle Present
TS24: lung Present
TS24: optic nerve Present
TS24: retina Present
TS24: tooth Present
TS24: brain Present Strongest in the cortex.

Specimen not shown: embryonic day 18.5 (more )
Note: Summarized in Table 1.
Structure Level Pattern Image Note
TS26: Meckel's cartilage Absent
TS26: dermis Absent
TS26: heart Absent
TS26: liver Absent
TS26: metanephros Absent
TS26: testis Absent
TS26: epidermis Strong
TS26: hair follicle Strong
TS26: nasal cavity epithelium Strong
TS26: oral epithelium Strong
TS26: rectum epithelium Strong
TS26: stomach mucosa Strong
TS26: submandibular gland Strong
TS26: tibia Strong
TS26: tongue epithelium Strong
TS26: tooth Strong
TS26: urethra epithelium Strong
TS26: vibrissa follicle Strong
TS26: cartilage condensation Present
TS26: lung Present
TS26: brain Present Strongest in the cortex.

Specimen not shown: embryonic day 19.5 (more )
Note: Summarized in Table 1.
Structure Level Pattern Image Note
TS26: Meckel's cartilage Absent
TS26: dermis Absent
TS26: heart Absent
TS26: liver Absent
TS26: metanephros Absent
TS26: testis Absent
TS26: epidermis Strong
TS26: hair follicle Strong
TS26: nasal cavity epithelium Strong
TS26: oral epithelium Strong
TS26: rectum epithelium Strong
TS26: submandibular gland Strong
TS26: tibia Strong
TS26: tongue epithelium Strong
TS26: tooth Strong
TS26: urethra epithelium Strong
TS26: urothelium of bladder Strong
TS26: vibrissa follicle Strong
TS26: pubis Present Regionally restricted Expressed in remaining cartilage elements.
TS26: trachea Present Regionally restricted Expressed in remaining cartilage elements.
TS26: cartilage condensation Present
TS26: brain Present Strongest in the cortex.


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
09/17/2024
MGI 6.24
The Jackson Laboratory