Tg(Sox10-cre)1Sout
Transgene Detail
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| Symbol: |
Tg(Sox10-cre)1Sout |
| Name: |
transgene insertion 1, E Southard-Smith |
| MGI ID: |
MGI:5897484 |
| Synonyms: |
Sox10-CrehGH, Tg(Sox10-CrehGH)1Sout |
| Transgene: |
Tg(Sox10-cre)1Sout Location: unknown
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| Alliance: |
Tg(Sox10-cre)1Sout page
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| Strain of Origin: |
(C57BL/6 x SJL)F2
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| Transgene Type: |
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Transgenic (Recombinase) |
| Mutation: |
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Insertion
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Tg(Sox10-cre)1Sout expression driven by
1 gene
Transgene expression driven by:
| Organism |
Driver Gene |
Note |
| Not Specified |
Sox10 |
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Mutation details: Using the BAC containing Sox10 regulatory regions, a nuclear localization sequence-modified Cre recombinase gene and a fragment from the human growth hormone gene was inserted directly downstream of the transcription initiation site. LoxP sites in the BAC flanking arms were removed prior to microinjection. The Sox10 regulatory regions drives neural crest-specifc expression of Cre recombinase.
(J:240668)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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Sox10
(species not specified)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:240668 Musser MA, et al., Enteric neuron imbalance and proximal dysmotility in ganglionated intestine of the Sox10Dom/+ Hirschsprung mouse model. Cell Mol Gastroenterol Hepatol. 2015 Jan 01;1(1):87-101 |
| All: |
3 reference(s) |
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Analysis Tools
