Tprn<em1Pghu> Endonuclease-mediated Allele Detail MGI Mouse (MGI:5897817)

Tprn^em1Pghu
Endonuclease-mediated Allele Detail

Summary

Symbol:	Tprn^em1Pghu
Name:	taperin; endonuclease-mediated mutation 1, Peng Hu
MGI ID:	MGI:5897817
Gene:	Tprn Location: Chr2:25152630-25159897 bp, + strand Genetic Position: Chr2, 17.11 cM
Alliance:	Tprn^em1Pghu page

Mutation
origin

Strain of Origin:

Not Specified

Mutation
description

Allele Type:		Endonuclease-mediated (Null/knockout)
Mutation:		Intragenic deletion
		TALEN technology induced a 1 bp deletion in exon 1. (J:240563)

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Disease models

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available
Carrying any Tprn Mutation:	19 strains or lines available

References

Original:	J:240563 Chen M, et al., Progressive hearing loss and degeneration of hair cell stereocilia in taperin gene knockout mice. Biochem Biophys Res Commun. 2016 Oct 28;479(4):703-707
All:	1 reference(s)

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