Tg(Cyp11a1-cre)30Mchu
Transgene Detail
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| Symbol: |
Tg(Cyp11a1-cre)30Mchu |
| Name: |
transgene insertion 30, Meng-Chun Hu |
| MGI ID: |
MGI:5898036 |
| Synonyms: |
Scc-icre, Tg(Cyp11a-cre)30Mchu |
| Transgene: |
Tg(Cyp11a1-cre)30Mchu Location: unknown
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| Alliance: |
Tg(Cyp11a1-cre)30Mchu page
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| Transgene Type: |
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Transgenic (Recombinase) |
| Mutation: |
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Insertion
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Tg(Cyp11a1-cre)30Mchu expression driven by
1 gene
Transgene expression driven by:
| Organism |
Driver Gene |
Note |
| Not Specified |
Cyp11a1 |
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Mutation details: This transgene uses the cytochrome P450, family 11, subfamily a, polypeptide 1 promoter to drive expression of the codon-improved cre recombinase (iCre) in the adrenal cortex and gonads, as well as the diencephalons and midbrain. Two copies of the HS4 insulator sequences derived from chicken beta-globin LCR were inserted into the cassette either upstream or downstream of the construct in reverse direction. Lines 16 and 41 were also made and expressed at a similar high level and in a consistent pattern.
(J:121826)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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Cyp11a1
(species not specified)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:121826 Wu HS, et al., Human CYP11A1 promoter drives Cre recombinase expression in the brain in addition to adrenals and gonads. Genesis. 2007 Feb;45(2):59-65 |
| All: |
1 reference(s) |
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Analysis Tools
