Tg(LTF-EGFP/cre/PGR)11Klin
Transgene Detail
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| Symbol: |
Tg(LTF-EGFP/cre/PGR)11Klin |
| Name: |
transgene insertion 11, Kurt Lin |
| MGI ID: |
MGI:5898041 |
| Synonyms: |
Lf-GCrePR1e, Tg(LTF-EGFP/Cre/PR1e)11Klin |
| Transgene: |
Tg(LTF-EGFP/cre/PGR)11Klin Location: unknown
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| Alliance: |
Tg(LTF-EGFP/cre/PGR)11Klin page
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| Transgene Type: |
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Transgenic (Inducible, Recombinase, Reporter) |
| Inducer: |
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mifepristone |
| Mutation: |
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Insertion
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Tg(LTF-EGFP/cre/PGR)11Klin expression driven by
1 gene
Transgene expression driven by:
| Organism |
Driver Gene |
Homolog in Mouse |
Note |
| human |
LTF (4057) |
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Mutation details: A construct was generated with a triple-fusion sequence EGFP/cre/PGR (encoding EGFP, cre recombinase, and the human progesterone ligand-binding domain - aa F642-L901 of LBD). The fusion gene was cloned downstream of the human lactoferrin promoter (LTF). The LfB-GCrePR1e construct was used for microinjection and 12 founders were obtained. Four founders (#'s 7, 11, 15, and 27) were crossed to R26-lacZ reporter mice. Line 15 was used to generate most of the results in the original study.
(J:209793)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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LTF
(human)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:209793 Chen MR, et al., RU486-inducible recombination in the salivary glands of lactoferrin promoter-driven green fluorescent Cre transgenic mice. Genesis. 2010 Oct 1;48(10):585-95 |
| All: |
1 reference(s) |
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Analysis Tools
