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Tg(Lck-cre)14Syt
Transgene Detail
Summary
Symbol: Tg(Lck-cre)14Syt
Name: transgene insertion 14, Huey-Kang Sytwu
MGI ID: MGI:5901740
Synonyms: Tg(Lck-cre)14Sytwu
Transgene: Tg(Lck-cre)14Syt  Location: unknown  
Alliance: Tg(Lck-cre)14Syt page
Transgene
origin
Strain of Origin:  NOD/ShiLtJSyt
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Lck-cre)14Syt expression driven by 1 gene
 
Mutation detailsA transgene construct containing proximal lymphocyte protein tyrosine kinase (Lck) promoter driving cre recombinase was used to create transgenic line in NOT/Sytwu mouse. At least two lines 7 and 14 were made. Cre recombinase is expressed in a T-cell specific manner. (J:194560, J:202955)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Lck (species not specified)
Summary of all recombinase alleles driven by Lck.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:194560 Lin MH, et al., B lymphocyte-induced maturation protein 1 (BLIMP-1) attenuates autoimmune diabetes in NOD mice by suppressing Th1 and Th17 cells. Diabetologia. 2013 Jan;56(1):136-46
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory