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Pck1tm2(EGFP/cre/ERT2)Wtsi
Targeted Allele Detail
Summary
Symbol: Pck1tm2(EGFP/cre/ERT2)Wtsi
Name: phosphoenolpyruvate carboxykinase 1, cytosolic; targeted mutation 2, Wellcome Trust Sanger Institute
MGI ID: MGI:5901752
Gene: Pck1  Location: Chr2:172994866-173001067 bp, + strand  Genetic Position: Chr2, 95.79 cM, cytoband C1-qter
Alliance: Pck1tm2(EGFP/cre/ERT2)Wtsi page
Mutation
origin
Mutant Cell Line:  CEPD0102_3_C04
Germline Transmission:  Earliest citation of germline transmission: J:188991
Parent Cell Line:  JM8A1.N3 (ES Cell)
Strain of Origin:  C57BL/6N-Atm1Brd
Project Collection: EUCOMMTOOLS
Mutation
description
Allele Type:    Targeted (Inducible, Recombinase, Reporter)
Inducer:    tamoxifen
Mutation:    Insertion     Vector: L1L2_gt1
 
Pck1tm2(EGFP/cre/ERT2)Wtsi expression driven by 1 gene
 
Mutation details: According to the allele molecular image presented by the International Knockout Mouse Consortium, this allele has inserted between exons 3 and 4 one FRT site followed by a splice acceptor then an EGFP followed by a cre/ERT2 and neomycin selection cassette, and there is one loxP site inserted between exons 5 and 6. (J:188991)
Inheritance:    Not Specified
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Pck1 (mouse)
Summary of all recombinase alleles driven by Pck1.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pck1 Mutation:  47 strains or lines available
References
Original:  J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012;
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory