Rttn In situ reporter (knock in) Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:76233 Faisst AM, et al., Rotatin is a novel gene required for axial rotation and left-right specification in mouse embryos. Mech Dev. 2002 Apr;113(1):15-28
Assay type:	In situ reporter (knock in)
MGI Accession ID:	MGI:5902693
Gene symbol:	Rttn
Gene name:	rotatin

Reporter:	lacZ
	Direct Detection

Results

2A +/- ©

Specimen 2A +/-: embryonic day 7.5; Rttn^{Gt(pGT1.8geo)7Pgr}/Rttn⁺ (more

)

Structure	Level	Pattern	Image	Note
TS11: embryo	Weak	Widespread	2A +/-
TS11: extraembryonic component	Weak	Widespread	2A +/-

2A -/- ©

Specimen 2A -/-: embryonic day 7.5; Rttn^{Gt(pGT1.8geo)7Pgr}/Rttn^{Gt(pGT1.8geo)7Pgr} (more

)

Structure	Level	Pattern	Image	Note
TS11: conceptus	Present		2A -/-

2B +/- ©

Specimen 2B +/-: embryonic day 8.5; Rttn^{Gt(pGT1.8geo)7Pgr}/Rttn⁺ (more

)

Structure	Level	Pattern	Image	Note
TS13: neural plate	Present	Regionally restricted	2B +/-
TS13: future prosencephalon	Strong	Regionally restricted	2B +/-	Strongest expression in telencephalon.
TS13: heart	Weak		2B +/-
TS13: somite	Weak		2B +/-

2E ©

Specimen 2E: embryonic day 9.5; Rttn^{Gt(pGT1.8geo)7Pgr}/Rttn⁺ (more

)

Structure	Level	Pattern	Image	Note
TS15: future forebrain	Present	Regionally restricted	2E	Expression in basal forebrain.
TS15: 1st branchial arch	Present		2E
TS15: forelimb bud	Present		2E
TS15: somite	Present		2E
TS15: heart	Absent		2E
TS15: tail	Absent		2E

2F ©

Specimen 2F: embryonic day 9.5; Rttn^{Gt(pGT1.8geo)7Pgr}/Rttn⁺ (more

)

Structure	Level	Pattern	Image	Note
TS15: somite	Present	Regionally restricted	2F	Expression in somites (particularly medial part).
TS15: forelimb bud mesenchyme	Present	Regionally restricted	2F
TS15: neural tube	Weak		2F
TS15: notochord	Weak		2F

2G ©

Specimen 2G: embryonic day 9.5; Rttn^{Gt(pGT1.8geo)7Pgr}/Rttn⁺ (more

)

Structure	Level	Pattern	Image	Note
TS15: somite	Present	Regionally restricted	2G	Expression in somites (particularly medial part) .
TS15: forelimb bud mesenchyme	Present		2G
TS15: neural tube	Weak		2G
TS15: notochord	Weak		2G
TS15: tail	Absent		2G

2H ©

Specimen 2H: embryonic day 9.5; Rttn^{Gt(pGT1.8geo)7Pgr}/Rttn⁺ (more

)

Structure	Level	Image
TS15: telencephalon	Present	2H
TS15: 1st branchial arch	Present	2H
TS15: 2nd branchial arch	Weak	2H

2I ©

Specimen 2I: embryonic day 9.5; Rttn^{Gt(pGT1.8geo)7Pgr}/Rttn⁺ (more

)

Structure	Level	Pattern	Image
TS15: future hindbrain	Present	Regionally restricted	2I
TS15: future midbrain	Present	Regionally restricted	2I
TS15: 1st branchial arch	Present		2I
TS15: 2nd branchial arch	Weak		2I

2J +/- ©

Specimen 2J +/-: embryonic day 11.5; Rttn^{Gt(pGT1.8geo)7Pgr}/Rttn⁺ (more

)

Structure	Level	Pattern	Image	Note
TS19: embryo mesoderm	Present	Regionally restricted	2J +/-	Authors state that mesodermal expression pattern is maintained.
TS19: branchial arch	Strong		2J +/-
TS19: heart	Present		2J +/-

3B -/- ©

Specimen 3B -/-: embryonic day 9.5; Rttn^{Gt(pGT1.8geo)7Pgr}/Rttn^{Gt(pGT1.8geo)7Pgr} (more

)

Structure	Level	Pattern	Image	Note
TS15: embryo	Present		3B -/-

3B +/- ©

Specimen 3B +/-: embryonic day 9.5; Rttn^{Gt(pGT1.8geo)7Pgr}/Rttn⁺ (more

)

Structure	Level	Pattern	Image	Note
TS15: embryo	Present		3B +/-

3H -/- ©

Specimen 3H -/-: embryonic day 10.5; Rttn^{Gt(pGT1.8geo)7Pgr}/Rttn^{Gt(pGT1.8geo)7Pgr} (more

)

Structure	Level	Pattern	Image	Note
TS17: embryo	Present		3H -/-

3H +/- ©

Specimen 3H +/-: embryonic day 10.5; Rttn^{Gt(pGT1.8geo)7Pgr}/Rttn⁺ (more

)

Structure	Level	Pattern	Image	Note
TS17: embryo	Present		3H +/-

3I -/- ©

Specimen 3I -/-: embryonic day 11.5; Rttn^{Gt(pGT1.8geo)7Pgr}/Rttn^{Gt(pGT1.8geo)7Pgr} (more

)

Structure	Level	Pattern	Image	Note
TS19: embryo	Present		3I -/-

3I +/- ©

Specimen 3I +/-: embryonic day 11.5; Rttn^{Gt(pGT1.8geo)7Pgr}/Rttn⁺ (more

)

Structure	Level	Pattern	Image	Note
TS19: embryo	Present		3I +/-

5D -/- ©

Specimen 5D -/-: embryonic day 8.5; Rttn^{Gt(pGT1.8geo)7Pgr}/Rttn^{Gt(pGT1.8geo)7Pgr} (more

)
Note: Double labeled: blue - Rttn reporter; purple - Foxa2 (assay MGI:5902704).

Structure	Level	Pattern	Image	Note
TS13: neural plate	Present		5D -/-

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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