About   Help   FAQ
Wnt10aem1(cre/ERT2)Amc
Endonuclease-mediated Allele Detail
Summary
Symbol: Wnt10aem1(cre/ERT2)Amc
Name: wingless-type MMTV integration site family, member 10A; endonuclease-mediated mutation 1, Andrew P McMahon
MGI ID: MGI:5902945
Synonyms: Wnt10a-CE, Wnt10aCRE-ERT2
Gene: Wnt10a  Location: Chr1:74831178-74843335 bp, + strand  Genetic Position: Chr1, 38.54 cM
Alliance: Wnt10aem1(cre/ERT2)Amc page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:159099
Parent Cell Line:  JM8.N4 (ES Cell)
Strain of Origin:  C57BL/6N
Mutation
description
Allele Type:    Endonuclease-mediated (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Wnt10aem1(cre/ERT2)Amc expression driven by 1 gene
 
Mutation details: Plasmids encoding a signal guide RNA designed to introduce a cre/ERT2 knock-in mutation into near the ATG site of the Wnt10a gene and the cas9 nuclease were introduced into the cytoplasm of C57BL/6N-derived JM8.N4 ES cells. (J:159099)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Wnt10a (mouse)
Summary of all recombinase alleles driven by Wnt10a.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Wnt10a Mutation:  19 strains or lines available
References
Original:  J:159099 McMahon A, et al., Summary of mouse strains characterized by GUDMAP consortium. Unpublished. 2010;
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory