Slc17a6tm1.1(flpo)Hze
Targeted Allele Detail
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| Symbol: |
Slc17a6tm1.1(flpo)Hze |
| Name: |
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6; targeted mutation 1.1, Hongkui Zeng |
| MGI ID: |
MGI:5903982 |
| Synonyms: |
Slc17a6-IRES2-FlpO-D, Vglut2-IRES2-FLPo-D |
| Gene: |
Slc17a6 Location: Chr7:51271754-51320867 bp, + strand Genetic Position: Chr7, 32.78 cM, cytoband B4
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| Alliance: |
Slc17a6tm1.1(flpo)Hze page
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| Allele Type: |
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Targeted (Recombinase) |
| Mutation: |
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Insertion
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Slc17a6tm1.1(flpo)Hze expression driven by
1 gene
Knock-in expression driven by:
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Mutation details: The targeting vector contains, from 5' to 3', a partial Slc17a6 sequence spanning exon 12 (including the endogenous stop codon), an internal ribosome entry site 2 sequence, a FlpO recombinase gene (a codon-optimized FLPe gene modified for translation in mammalian cells and higher recombination efficiency in cells and in mice), a bovine growth hormone polyA sequence, an AttB site, a PGK promoter-Neomycin resistance gene-PGK polyA cassette, an frt5 site, an mRNA splice acceptor sequence, the 3' portion of the hygromycin gene (Hygro2) with SV40 polyA signal, and an AttP site. PhiC31-mediated recombination removed the AttB/AttP-flanked sequence (PGK-Neo-polyA::frt5::RNA splice acceptor::3'hygro-polyA) and replaced it with the recombined AttB/AttP site (AttL).
(J:101977)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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Slc17a6
(mouse)
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| Original: |
J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017; |
| All: |
12 reference(s) |
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Analysis Tools
