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Gnrhrtm1.1(cre/ERT2)Djb
Targeted Allele Detail
Summary
Symbol: Gnrhrtm1.1(cre/ERT2)Djb
Name: gonadotropin releasing hormone receptor; targeted mutation 1.1, Daniel J Bernard
MGI ID: MGI:5908151
Synonyms: iGRIC
Gene: Gnrhr  Location: Chr5:86328613-86345760 bp, - strand  Genetic Position: Chr5, 43.56 cM
Alliance: Gnrhrtm1.1(cre/ERT2)Djb page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:262146
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Gnrhrtm1.1(cre/ERT2)Djb expression driven by 1 gene
    An IRES-cre/ERT2 and frt-flanked neo cassette were inserted downstream of exon 3. (J:262146)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Gnrhr (mouse)
Summary of all recombinase alleles driven by Gnrhr.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gnrhr Mutation:  20 strains or lines available
References
Original:  J:262146 Li Y, et al., Conditional deletion of FOXL2 and SMAD4 in gonadotropes of adult mice causes isolated FSH deficiency. Endocrinology. 2018 May 23;
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory