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Scd3tm1(icre)Msdr
Targeted Allele Detail
Summary
Symbol: Scd3tm1(icre)Msdr
Name: stearoyl-coenzyme A desaturase 3; targeted mutation 1, Marlon R Schneider
MGI ID: MGI:5908392
Synonyms: Scd3-Cre
Gene: Scd3  Location: Chr19:44191727-44232455 bp, + strand  Genetic Position: Chr19, 37.98 cM, cytoband D2
Alliance: Scd3tm1(icre)Msdr page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:235532
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
Scd3tm1(icre)Msdr expression driven by 1 gene
 
Mutation details: cDNA encoding icre (improved cre) was inserted into immediately before the first ATG in exon 1 of the mouse Scd3 gene by homologouse recombination in ES cell. (J:235532)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Scd3 (mouse)
Summary of all recombinase alleles driven by Scd3.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Scd3 Mutation:  16 strains or lines available
References
Original:  J:235532 Dahlhoff M, et al., Sebaceous lipids are essential for water repulsion, protection against UVB-induced apoptosis and ocular integrity in mice. Development. 2016 May 15;143(10):1823-31
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory