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Bhlha9tm1(Venus/cre)Asah
Targeted Allele Detail
Summary
Symbol: Bhlha9tm1(Venus/cre)Asah
Name: basic helix-loop-helix family, member a9; targeted mutation 1, Hiroshi Asahara
MGI ID: MGI:5909077
Synonyms: Bhlha9 KO
Gene: Bhlha9  Location: Chr11:76563296-76564502 bp, + strand  Genetic Position: Chr11, 45.97 cM
Alliance: Bhlha9tm1(Venus/cre)Asah page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:243551
Parent Cell Line:  TT2F (ES Cell)
Strain of Origin:  (C57BL/6NCrlj x CBA/JNCrlj)F1
Mutation
description
Allele Type:    Targeted (Null/knockout, Recombinase, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Bhlha9tm1(Venus/cre)Asah expression driven by 1 gene
 
Mutation detailsA vector was constructed for replacement of the endogenous Bhlha9 locus with the Venus-Cre and FRT flanked PGK-Neo cassette via homologous recombination in embryonic stem cells. Upon recombination, although genome mutation was confirmed by Southern blotting and PCR, Venus-Cre protein expression in limb bud was not detected. (J:243551)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Bhlha9 (mouse)
Summary of all recombinase alleles driven by Bhlha9.
 

Expression
In Mice Carrying this Mutation: 1 RNA-Seq or microarray experiment(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Bhlha9 Mutation:  10 strains or lines available
References
Original:  J:243551 Kataoka K, et al., Bhlha9 regulates apical ectodermal ridge formation during limb development. J Bone Miner Metab. 2018 Jan;36(1):64-72
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
08/02/2024
MGI 6.24
The Jackson Laboratory