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Galtm1(cre)Hmun
Targeted Allele Detail
Summary
Symbol: Galtm1(cre)Hmun
Name: galanin and GMAP prepropeptide; targeted mutation 1, Heike Munzberg
MGI ID: MGI:5909271
Synonyms: GalCre
Gene: Gal  Location: Chr19:3459915-3464544 bp, - strand  Genetic Position: Chr19, 3.16 cM
Alliance: Galtm1(cre)Hmun page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:243627
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
Galtm1(cre)Hmun expression driven by 1 gene
 
Mutation details: An IRES-cre sequence was inserted into the murine Gal gene between the Stop codon and polyadenylation site; an frt-flanked neo cassette was inserted downstream of the polyadenylation sites by homologous recombination in ES cells. (J:243627)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Gal (mouse)
Summary of all recombinase alleles driven by Gal.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gal Mutation:  23 strains or lines available
References
Original:  J:243627 Laque A, et al., Leptin modulates nutrient reward via inhibitory galanin action on orexin neurons. Mol Metab. 2015 Oct;4(10):706-17
All:  3 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory