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Tg(Stab2-icre)1.2Cger
Transgene Detail
Summary
Symbol: Tg(Stab2-icre)1.2Cger
Name: transgene insertion 1.2, Cyrill Geraud
MGI ID: MGI:5909287
Synonyms: Stab2-Cre, Stab2tg1.2cre
Transgene: Tg(Stab2-icre)1.2Cger  Location: unknown  
Alliance: Tg(Stab2-icre)1.2Cger page
Transgene
origin
Strain of Origin:  C57BL/6NCrl
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Stab2-icre)1.2Cger expression driven by 1 gene
 
Mutation details: A cDNA containing a codon improved version of cre recombinase followed by polyA signal sequence was fused into BAC clone at exon 1 of mouse Stab2 gene so that cre expression is driven by the regulatory sequences of the BAC gene. The resulting modified BAC was used to generate this transgene. Three founder lines 1.1, 1.2, and 1.3 were identified. The line 1.2 displaying cre activity in liver sinusoidal endothelial cells were used for the study. (J:243226)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Stab2 (mouse)
Summary of all recombinase alleles driven by Stab2.
 

Expression
In Mice Carrying this Mutation: 1 RNA-Seq or microarray experiment(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:243226 Geraud C, et al., GATA4-dependent organ-specific endothelial differentiation controls liver development and embryonic hematopoiesis. J Clin Invest. 2017 Mar 01;127(3):1099-1114
All:  3 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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11/12/2024
MGI 6.24 		The Jackson Laboratory