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Sox14tm2.1(cre)Tmj
Targeted Allele Detail
Summary
Symbol: Sox14tm2.1(cre)Tmj
Name: SRY (sex determining region Y)-box 14; targeted mutation 2.1, Thomas M Jessell
MGI ID: MGI:5909921
Synonyms: Sox14::Cre
Gene: Sox14  Location: Chr9:99756159-99758223 bp, - strand  Genetic Position: Chr9, 52.11 cM
Alliance: Sox14tm2.1(cre)Tmj page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:243238
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S/SvEv
Mutation
description
Allele Type:    Targeted (Null/knockout, Recombinase)
Mutations:    Insertion, Intragenic deletion
 
Sox14tm2.1(cre)Tmj expression driven by 1 gene
 
Mutation details: The targeting vector was constructed by replacing the Sox14 coding sequence with a cassette consisting of a 5' splice substrate followed by the cre gene and a bovine growth hormone polyadenylation signal (bGHpA) followed by a Frt flanked neomycin gene cassette by homologouse recombination in ES cells. The PGKneo cassette was removed after crossing with the FLPeR mice. (J:243238)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Sox14 (mouse)
Summary of all recombinase alleles driven by Sox14.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Sox14 Mutation:  14 strains or lines available
References
Original:  J:243238 Jager P, et al., Tectal-derived interneurons contribute to phasic and tonic inhibition in the visual thalamus. Nat Commun. 2016 Dec 08;7:13579
All:  4 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory