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Tg(Agrp-cre/ERT2)#Jmz
Transgene Detail
Summary
Symbol: Tg(Agrp-cre/ERT2)#Jmz
Name: transgene insertion, Jeffrey M Zigman
MGI ID: MGI:5909993
Synonyms: AgRP-CreERT2
Transgene: Tg(Agrp-cre/ERT2)#Jmz  Location: unknown  
Alliance: Tg(Agrp-cre/ERT2)#Jmz page
Transgene
origin
Strain of Origin:  C57BL/6J
Transgene
description
Transgene Type:    Transgenic (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Tg(Agrp-cre/ERT2)#Jmz expression driven by 1 gene
 
Mutation detailsThe transgene contains BAC into which an inducible cre recombinase gene (cre/ERT2) was introduced at the start site to replace the coding sequence of the Agrp gene. The linearized vector was injected into C57BL/6J fertilized oocytes. Founder information and line numbers were not available. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:221292)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Agrp (species not specified)
Summary of all recombinase alleles driven by Agrp.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:221292 Wang Q, et al., Arcuate AgRP neurons mediate orexigenic and glucoregulatory actions of ghrelin. Mol Metab. 2014 Feb;3(1):64-72
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory