Tg(Agrp-cre/ERT2)#Jmz
Transgene Detail
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Symbol: |
Tg(Agrp-cre/ERT2)#Jmz |
Name: |
transgene insertion, Jeffrey M Zigman |
MGI ID: |
MGI:5909993 |
Synonyms: |
AgRP-CreERT2 |
Transgene: |
Tg(Agrp-cre/ERT2)#Jmz Location: unknown
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Alliance: |
Tg(Agrp-cre/ERT2)#Jmz page
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Transgene Type: |
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Transgenic (Inducible, Recombinase) |
Inducer: |
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tamoxifen |
Mutation: |
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Insertion
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Tg(Agrp-cre/ERT2)#Jmz expression driven by
1 gene
Transgene expression driven by:
Organism |
Driver Gene |
Note |
Not Specified |
Agrp |
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Mutation details: The transgene contains BAC into which an inducible cre recombinase gene (cre/ERT2) was introduced at the start site to replace the coding sequence of the Agrp gene. The linearized vector was injected into C57BL/6J fertilized oocytes. Founder information and line numbers were not available. The pound symbol (#) is used when no line is specified and/or lines are pooled.
(J:221292)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Agrp
(species not specified)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Original: |
J:221292 Wang Q, et al., Arcuate AgRP neurons mediate orexigenic and glucoregulatory actions of ghrelin. Mol Metab. 2014 Feb;3(1):64-72 |
All: |
5 reference(s) |
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