Mslntm1.1(cre/ERT2)Ilw
Targeted Allele Detail
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Symbol: |
Mslntm1.1(cre/ERT2)Ilw |
Name: |
mesothelin; targeted mutation 1.1, Irving L Weissman |
MGI ID: |
MGI:5910114 |
Synonyms: |
MslnCLN, MslnnLacZ-ER-Cre |
Gene: |
Msln Location: Chr17:25967587-25973352 bp, - strand Genetic Position: Chr17, 12.85 cM, cytoband A3.3
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Alliance: |
Mslntm1.1(cre/ERT2)Ilw page
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Germline Transmission: |
Earliest citation of germline transmission:
J:195251
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
Not Specified
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Allele Type: |
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Targeted (Inducible, Null/knockout, Recombinase, Reporter) |
Inducer: |
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tamoxifen |
Mutations: |
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Insertion, Intragenic deletion
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Mslntm1.1(cre/ERT2)Ilw expression driven by
1 gene
Knock-in expression driven by:
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Mutation details: The ATG start codon of Msln gene was replaced by the CreERT2-IRES-lacZ-polyA signal and FRT-flanked PGKneo cassetter in exon 1. CThe neo cassette was laater removed by crossing with Flpe-expressing mice.
(J:195251)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Msln
(mouse)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Msln Mutation: |
38 strains or lines available
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Original: |
J:195251 Rinkevich Y, et al., Identification and prospective isolation of a mesothelial precursor lineage giving rise to smooth muscle cells and fibroblasts for mammalian internal organs, and their vasculature. Nat Cell Biol. 2012 Dec;14(12):1251-60 |
All: |
3 reference(s) |
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