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Tg(Tff1-cre/ERT2)#Ern
Transgene Detail
Summary
Symbol: Tg(Tff1-cre/ERT2)#Ern
Name: transgene insertion, Matthias Ernst
MGI ID: MGI:5911315
Transgene: Tg(Tff1-cre/ERT2)#Ern  Location: unknown  
Alliance: Tg(Tff1-cre/ERT2)#Ern page
Transgene
origin
Strain of Origin:  (C57BL/6 x CBA)F1
Transgene
description
Transgene Type:    Transgenic (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Tg(Tff1-cre/ERT2)#Ern expression driven by 1 gene
 
Mutation detailsBAC recombineering was used to generate a vector with the CreERT2 open reading frame with a polyadenylation signal inserted immediately downstream of the endogenous ATG initiation codon in the Tff1 locus. The purified construct was used for pronuclear injection to generate transgenic lines. Line numbers were not indicated. (J:231629)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Tff1 (species not specified)
Summary of all recombinase alleles driven by Tff1.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:231629 Thiem S, et al., Stomach-Specific Activation of Oncogenic KRAS and STAT3-Dependent Inflammation Cooperatively Promote Gastric Tumorigenesis in a Preclinical Model. Cancer Res. 2016 Apr 15;76(8):2277-87
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory