Tg(Tff1-cre/ERT2)#Ern
Transgene Detail
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Symbol: |
Tg(Tff1-cre/ERT2)#Ern |
Name: |
transgene insertion, Matthias Ernst |
MGI ID: |
MGI:5911315 |
Transgene: |
Tg(Tff1-cre/ERT2)#Ern Location: unknown
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Alliance: |
Tg(Tff1-cre/ERT2)#Ern page
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Transgene Type: |
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Transgenic (Inducible, Recombinase) |
Inducer: |
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tamoxifen |
Mutation: |
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Insertion
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Tg(Tff1-cre/ERT2)#Ern expression driven by
1 gene
Transgene expression driven by:
Organism |
Driver Gene |
Note |
Not Specified |
Tff1 |
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Mutation details: BAC recombineering was used to generate a vector with the CreERT2 open reading frame with a polyadenylation signal inserted immediately downstream of the endogenous ATG initiation codon in the Tff1 locus. The purified construct was used for pronuclear injection to generate transgenic lines. Line numbers were not indicated.
(J:231629)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Tff1
(species not specified)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Original: |
J:231629 Thiem S, et al., Stomach-Specific Activation of Oncogenic KRAS and STAT3-Dependent Inflammation Cooperatively Promote Gastric Tumorigenesis in a Preclinical Model. Cancer Res. 2016 Apr 15;76(8):2277-87 |
All: |
7 reference(s) |
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