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Rnaseh2ctm1Roer
Targeted Allele Detail
Summary
Symbol: Rnaseh2ctm1Roer
Name: ribonuclease H2, subunit C; targeted mutation 1, Axel Roers
MGI ID: MGI:5911394
Gene: Rnaseh2c  Location: Chr19:5651901-5652987 bp, + strand  Genetic Position: Chr19, 4.34 cM, cytoband A
Alliance: Rnaseh2ctm1Roer page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:186986
Parent Cell Line:  JM8.F6 (ES Cell)
Strain of Origin:  C57BL/6N
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    A neomycin resistance cassette replaced the 4 coding exons. (J:186986)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rnaseh2c Mutation:  10 strains or lines available
References
Original:  J:186986 Hiller B, et al., Mammalian RNase H2 removes ribonucleotides from DNA to maintain genome integrity. J Exp Med. 2012 Jul 30;209(8):1419-26
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory