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Dmbx1tm2(cre/ERT2)Miki
Targeted Allele Detail
Summary
Symbol: Dmbx1tm2(cre/ERT2)Miki
Name: diencephalon/mesencephalon homeobox 1; targeted mutation 2, Takashi Miki
MGI ID: MGI:5911627
Synonyms: Dmbx1creERT2
Gene: Dmbx1  Location: Chr4:115772316-115797123 bp, - strand  Genetic Position: Chr4, 53.07 cM
Alliance: Dmbx1tm2(cre/ERT2)Miki page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:233637
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Inducible, Recombinase)
Inducer:    tamoxifen
Mutations:    Insertion, Intragenic deletion
 
Dmbx1tm2(cre/ERT2)Miki expression driven by 1 gene
 
Mutation details: A vector coding for a splice acceptor, IRES, and Cre/ERT2 fusion protein and neo selection cassette replaced a portion of exon 2 immidiately after ATG translation initiation site of Dmbx1 gene via homologous recombination. (J:233637)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Dmbx1 (mouse)
Summary of all recombinase alleles driven by Dmbx1.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Dmbx1 Mutation:  20 strains or lines available
References
Original:  J:233637 Hirono S, et al., Importance of Adult Dmbx1 in Long-Lasting Orexigenic Effect of Agouti-Related Peptide. Endocrinology. 2016 Jan;157(1):245-57
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory