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Runx3tm6(EGFP/cre)Yg
Targeted Allele Detail
Summary
Symbol: Runx3tm6(EGFP/cre)Yg
Name: runt related transcription factor 3; targeted mutation 6, Yoram Groner
MGI ID: MGI:5911702
Synonyms: Runx3Cre
Gene: Runx3  Location: Chr4:134847963-134905301 bp, + strand  Genetic Position: Chr4, 67.19 cM
Alliance: Runx3tm6(EGFP/cre)Yg page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:241125
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)
Mutation
description
Allele Type:    Targeted (Recombinase, Reporter)
Mutation:    Insertion
 
Runx3tm6(EGFP/cre)Yg expression driven by 1 gene
 
Mutation details: A EGFP-Cre-CSF-PolyAfrt-Pgk/neo-frt cassette was inserted in-frame into exon 4 via homologous recombination in ES cells. (J:241125)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Runx3 (mouse)
Summary of all recombinase alleles driven by Runx3.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 4 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Runx3 Mutation:  27 strains or lines available
References
Original:  J:241125 Levanon D, et al., Absence of Runx3 expression in normal gastrointestinal epithelium calls into question its tumour suppressor function. EMBO Mol Med. 2011 Oct;3(10):593-604
All:  3 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory