Tg(Pax8-cre/ERT2)CAmat
Transgene Detail
|
|
| Symbol: |
Tg(Pax8-cre/ERT2)CAmat |
| Name: |
transgene insertion C, Athena Matakidou |
| MGI ID: |
MGI:5911838 |
| Synonyms: |
Pax8-CreERT2 |
| Transgene: |
Tg(Pax8-cre/ERT2)CAmat Location: unknown Genetic Position: Chr6, cytoband 6qC1
|
| Alliance: |
Tg(Pax8-cre/ERT2)CAmat page
|
|
|
|
| Transgene Type: |
|
Transgenic (Inducible, Recombinase) |
| Inducer: |
|
tamoxifen |
| Mutation: |
|
Insertion
|
| |
|
Tg(Pax8-cre/ERT2)CAmat expression driven by
1 gene
Transgene expression driven by:
| Organism |
Driver Gene |
Note |
| mouse |
Pax8 (MGI:97492) |
|
|
| |
|
Mutation details: A DNA fragment encoding the cre/ERT2 fusion protein with a poly A sequence was inserted at the endogenous ATG translational start site of a murine Pax8 sequence. The construct was injected into C57BL/6J blastocysts. Five transgenic founders were identified, and data for one of them (Line C) is reported. The transgene integration in this line was localized via fluorescence in situ hybridization and paired-end whole genome sequencing to an intergenic region of Chr 6qC1 (chr6:62,912,590-62,912,610; GRCh38/mm10).
(J:243751)
|
|
|
|
Activity: |
 Tissue activity of this recombinase allele
|
|
Driver:
|
Pax8
(mouse)
|
| |
|
|
| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 2 strains available
Cell Lines: 0 lines available
|
|
| Original: |
J:243751 Espana-Agusti J, et al., Generation and Characterisation of a Pax8-CreERT2 Transgenic Line and a Slc22a6-CreERT2 Knock-In Line for Inducible and Specific Genetic Manipulation of Renal Tubular Epithelial Cells. PLoS One. 2016;11(2):e0148055 |
| All: |
3 reference(s) |
|
Analysis Tools
