Tg(Myh6-Sgcd*S151A)5Mcn
Transgene Detail
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| Symbol: |
Tg(Myh6-Sgcd*S151A)5Mcn |
| Name: |
transgene insertion 5, Elizabeth M McNally |
| MGI ID: |
MGI:5911918 |
| Transgene: |
Tg(Myh6-Sgcd*S151A)5Mcn Location: unknown
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| Alliance: |
Tg(Myh6-Sgcd*S151A)5Mcn page
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| Strain of Origin: |
Not Specified
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| Transgene Type: |
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Transgenic (Inserted expressed sequence) |
| Mutation: |
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Insertion
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Tg(Myh6-Sgcd*S151A)5Mcn expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Note |
| Not Specified |
Sgcd |
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Mutation details: Delta-sarcoglycan, in which the serine at amino acid position 151 was mutated into an alanine (S151A), is under the control of the cardiac-specific alpha-myosin heavy chain promoter. Five lines were generated (1-5), however only line 5 could be maintained due to perinatal lethality in the other lines.
(J:117855)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:117855 Heydemann A, et al., Nuclear sequestration of {delta}-sarcoglycan disrupts the nuclear localization of lamin A/C and emerin in cardiomyocytes. Hum Mol Genet. 2007 Feb 15;16(4):355-63 |
| All: |
1 reference(s) |
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Analysis Tools
