Hinfp In situ reporter (knock in) Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:237226 Ghule PN, et al., Maternal expression and early induction of histone gene transcription factor Hinfp sustains development in pre-implantation embryos. Dev Biol. 2016 Nov 15;419(2):311-320
Assay type:	In situ reporter (knock in)
MGI Accession ID:	MGI:5912160
Gene symbol:	Hinfp
Gene name:	histone H4 transcription factor

Reporter:	lacZ
	Direct Detection

Results

1A KO left ©

Specimen A KO left: embryonic day 4.5; Hinfp^tm1Gss/Hinfp^tm1Gss (more

)

Structure	Level	Pattern	Image	Note
TS6: embryo	Present		1A KO left

1A HET ©

Specimen A HET: embryonic day 4.5; Hinfp^tm1Gss/Hinfp⁺ (more

)

Structure	Level	Pattern	Image	Note
TS6: embryo	Present		1A HET

1A KO right ©

Specimen A KO right: embryonic day 4.5; Hinfp^tm1Gss/Hinfp^tm1Gss (more

)

Structure	Level	Pattern	Image	Note
TS6: embryo	Present		1A KO right

4A top left ©

Specimen 4A top left: embryonic day 3.5; Hinfp^tm1Gss/Hinfp⁺ (more

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Note: This embryo is result of a cross between a WT male and a heterozygote female. Expression is inherited maternally.

Structure	Level	Pattern	Image	Note
TS5: inner cell mass	Present		4A top left

Specimen 4A bottom left: embryonic day 3.5; Hinfp^tm1Gss/Hinfp⁺ (more

)
Note: This embryo is the result of a cross between a heterozygous male and a WT female.

Structure	Level	Pattern	Image	Note
TS5: inner cell mass	Present		4A bottom left

Specimen 4B E2.5 bottom right: embryonic day 2.5; Hinfp^tm1Gss/Hinfp⁺ (more

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Note: 8-cell stage embryo. This embryo is the result of a cross between a heterozygous male and a WT female.

Structure	Level	Pattern	Image	Note
TS3: 8-cell stage embryo	Present		4B E2.5 bottom right

Specimen 4B E2 bottom right: embryonic day 2.0; Hinfp^tm1Gss/Hinfp⁺ (more

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Note: 4-cell stage embryo. This embryo is the result of a cross between a heterozygous male and a WT female.

Structure	Level	Pattern	Image	Note
TS3: 4-cell stage embryo	Present		4B E2 bottom right

Specimen 4B E1.5 bottom: embryonic day 1.5; Hinfp^tm1Gss/Hinfp⁺ (more

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Note: 2-cell stage embryo. This embryo is the result of a cross between a heterozygous male and a WT female.

Structure	Level	Pattern	Image	Note
TS2: 2-cell stage embryo	Absent		4B E1.5 bottom

Specimen 4C Het top: postnatal; Hinfp^tm1Gss/Hinfp⁺ (more

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Note: Fixative was 0.5% glutaraldehyde.

Structure	Level	Pattern	Image	Note
TS28: oocyte	Strong		4C Het top right , 4C Het top left	Expression is in the nucleus.

Specimen 4C Het bottom: postnatal; Hinfp^tm1Gss/Hinfp⁺ (more

)
Note: Fixative was 0.5% glutaraldehyde.

Structure	Level	Pattern	Image	Note
TS28: oocyte	Strong		4C Het bottom right , 4C Het bottom left	Expression is in the nucleus.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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