Tg(Sost-GFP/cre)#Caob
Transgene Detail
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| Symbol: |
Tg(Sost-GFP/cre)#Caob |
| Name: |
transgene insertion, Charles A O'Brien |
| MGI ID: |
MGI:5922035 |
| Synonyms: |
Tg(Sost,GFP/cre)#Caob, Tg(Sost[RP24-276023]-GFP/Cre) |
| Transgene: |
Tg(Sost-GFP/cre)#Caob Location: unknown
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| Alliance: |
Tg(Sost-GFP/cre)#Caob page
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| Transgene Type: |
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Transgenic (Recombinase, Reporter) |
| Mutation: |
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Insertion
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Tg(Sost-GFP/cre)#Caob expression driven by
1 gene
Transgene expression driven by:
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Mutation details: A green fluorescent protein (GFP)-cre recombinase fusion protein, preceded by an internal ribosome entry site (IRES), was inserted into the second exon of the murine gene in BAC clone RP24-276O23, replacing most of the 3' UTR. The engineered BAC DNA was microinjected into fertilized C57BL/6 oocytes. Four independent founder lines were generated, of which one was used for further study. The pound # sign is used in the allele symbol because the line used was not specified.
(J:243173)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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Sost
(mouse)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:243173 Xiong J, et al., Osteocytes, not Osteoblasts or Lining Cells, are the Main Source of the RANKL Required for Osteoclast Formation in Remodeling Bone. PLoS One. 2015;10(9):e0138189 |
| All: |
2 reference(s) |
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Analysis Tools
