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Tuba8tm1.1Ctpd
Targeted Allele Detail
Summary
Symbol: Tuba8tm1.1Ctpd
Name: tubulin, alpha 8; targeted mutation 1.1, Christine P Diggle
MGI ID: MGI:6094270
Gene: Tuba8  Location: Chr6:121187655-121203813 bp, + strand  Genetic Position: Chr6, 57.15 cM, cytoband F1
Alliance: Tuba8tm1.1Ctpd page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:248203
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsAn FRT-flanked neomycin with a 5' lox site was inserted upstream of exon 3. An additional loxP site was inserted downstream of exon 3. Flp-mediated recombination removed the selection cassette and left exon 3 floxed. (J:248203)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tuba8 Mutation:  28 strains or lines available
References
Original:  J:248203 Diggle CP, et al., A tubulin alpha 8 mouse knockout model indicates a likely role in spermatogenesis but not in brain development. PLoS One. 2017;12(4):e0174264
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory