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Gene Expression Data
Assay Details
Assay
Reference: J:71587 Potterf SB, et al., Analysis of sox10 function in neural crest-derived melanocyte development: sox10-dependent transcriptional control of dopachrome tautomerase. Dev Biol. 2001 Sep 15;237(2):245-57
Assay type: RNA in situ
MGI Accession ID: MGI:6094898
Gene symbol: Dct
Gene name: dopachrome tautomerase
Probe: Dct probe5
Probe preparation: Antisense RNA
Results
Specimen 1A: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: head surface ectoderm Present Regionally restricted 1A Expression is in melanoblasts.
TS19: pigmented retinal epithelium Present 1A

Specimen 1B: embryonic day 11.5; Sox10Dom/Sox10+ (more )
Structure Level Pattern Image Note
TS19: pigmented retinal epithelium Present 1B
TS19: head surface ectoderm Trace Single cells 1B Expression is in an occasional cell around the otocyst or head.

Specimen 1C: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: pinna Present Regionally restricted 1C Expression is in melanoblasts.

Specimen 1D: embryonic day 12.5; Sox10Dom/Sox10+ (more )
Structure Level Pattern Image Note
TS20: pinna Absent 1D Expression is in melanoblasts which are almost entirely lacking in this mutant.

Specimen 1E: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: trunk surface ectoderm Present Regionally restricted 1E Expression is in melanoblasts.

Specimen 1F: embryonic day 11.5; Sox10Dom/Sox10+ (more )
Structure Level Pattern Image Note
TS19: trunk surface ectoderm Absent 1F Expression is in melanoblasts which are almost entirely lacking in this mutant.

Specimen 1G: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: trunk Present Regionally restricted 1G Expression is in melanoblasts.

Specimen 1H: embryonic day 12.5; Sox10Dom/Sox10+ (more )
Structure Level Pattern Image Note
TS20: trunk Absent 1H

Specimen 1I: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: head skin Present Regionally restricted 1I Expression is in melanoblasts.
TS21: pigmented retinal epithelium Present 1I

Specimen 1J: embryonic day 13.5; Sox10Dom/Sox10+ (more )
Structure Level Pattern Image Note
TS21: head skin Present Regionally restricted 1J Expression is in melanoblasts. The number of melanoblasts is reduced in this mutant compared to wild-type.
TS21: pigmented retinal epithelium Present 1J

Specimen 1K: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: trunk Present Regionally restricted 1K Expression is in melanoblasts.

Specimen 1L: embryonic day 13.5; Sox10Dom/Sox10+ (more )
Structure Level Pattern Image Note
TS21: trunk Present Regionally restricted 1L Expression is in melanoblasts. The number of melanoblasts is reduced in this mutant compared to wild-type.

Specimen not shown E11.5: embryonic day 11.5; Sox10Dom/Sox10+ (more )
Structure Level Pattern Image Note
TS19: tail surface ectoderm Trace Regionally restricted Very few expressing melanocytes are only seen in the most caudal region in this mutant.

Specimen not shown E12.5: embryonic day 12.5; Sox10Dom/Sox10+ (more )
Structure Level Pattern Image Note
TS20: tail surface ectoderm Trace Regionally restricted Very few expressing melanocytes are only seen in the most caudal region in this mutant.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
06/12/2024
MGI 6.13
The Jackson Laboratory