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Rasgrp1tm2(GFP/cre/ERT2)Wtsi
Targeted Allele Detail
Summary
Symbol: Rasgrp1tm2(GFP/cre/ERT2)Wtsi
Name: RAS guanyl releasing protein 1; targeted mutation 2, Wellcome Trust Sanger Institute
MGI ID: MGI:6095165
Synonyms: tm2(EGFP_CreERT2)Wtsi
Gene: Rasgrp1  Location: Chr2:117110464-117173358 bp, - strand  Genetic Position: Chr2, 59.19 cM
Alliance: Rasgrp1tm2(GFP/cre/ERT2)Wtsi page
Mutation
origin
Mutant Cell Line:  CEPD0102_2_D10
Germline Transmission:  Earliest citation of germline transmission: J:188991
Parent Cell Line:  JM8A1.N3 (ES Cell)
Strain of Origin:  C57BL/6N-Atm1Brd
Project Collection: EUCOMMTOOLS
Mutation
description
Allele Type:    Targeted (Inducible, Recombinase, Reporter)
Inducer:    tamoxifen
Mutation:    Insertion     Vector: L1L2_gt1
 
Rasgrp1tm2(GFP/cre/ERT2)Wtsi expression driven by 1 gene
 
Mutation details: According to the vector molecular image presented by the International Knockout Mouse Consortium, this allele has one FRT site, an engrailed 2 splice acceptor sequence, an EGFP and cre/ERT2 expression cassette, and a neomycin resistance cassette inserted into the intron just upstream of exon 3, and a single loxP site just downstream of exon 3. (J:188991)
Inheritance:    Not Specified
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Rasgrp1 (mouse)
Summary of all recombinase alleles driven by Rasgrp1.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rasgrp1 Mutation:  57 strains or lines available
References
Original:  J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012;
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory