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Gsdma2tm1(GFP/cre/ERT2)Wtsi
Targeted Allele Detail
Summary
Symbol: Gsdma2tm1(GFP/cre/ERT2)Wtsi
Name: gasdermin A2; targeted mutation 1, Wellcome Trust Sanger Institute
MGI ID: MGI:6095194
Synonyms: tm1(EGFP_CreERT2)Wtsi
Gene: Gsdma2  Location: Chr11:98537585-98548790 bp, + strand  Genetic Position: Chr11, 62.28 cM, cytoband D
Alliance: Gsdma2tm1(GFP/cre/ERT2)Wtsi page
Mutation
origin
Mutant Cell Line:  CEPD0108_3_C09
Germline Transmission:  Earliest citation of germline transmission: J:188991
Parent Cell Line:  JM8A3.N1 (ES Cell)
Strain of Origin:  C57BL/6N-Atm1Brd
Project Collection: EUCOMMTOOLS
Mutation
description
Allele Type:    Targeted (Conditional ready, Inducible, Recombinase, Reporter)
Inducer:    tamoxifen
Mutation:    Insertion
 
Gsdma2tm1(GFP/cre/ERT2)Wtsi expression driven by 1 gene
 
Mutation detailsAccording to the vector molecular image presented by the International Knockout Mouse Consortium, this allele has one FRT site, an engrailed 2 splice acceptor sequence, an EGFP and cre/ERT2 expression cassette, a Rox-flanked puromycin resistance cassette followed by one loxP site all inserted into the intron just upstream of exon 5, and a single loxP site downstream of exon 7. (J:188991)
Inheritance:    Not Specified
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Gsdma2 (mouse)
Summary of all recombinase alleles driven by Gsdma2.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gsdma2 Mutation:  31 strains or lines available
References
Original:  J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory