Tg(Tbx6-cre/ERT2)1Pa
Transgene Detail
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| Symbol: |
Tg(Tbx6-cre/ERT2)1Pa |
| Name: |
transgene insertion 1, Virginia Papaioannou |
| MGI ID: |
MGI:6105951 |
| Synonyms: |
Tbx6-creERT2, Tg(Tbx6-creERT2)1Pa |
| Transgene: |
Tg(Tbx6-cre/ERT2)1Pa Location: unknown
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| Alliance: |
Tg(Tbx6-cre/ERT2)1Pa page
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| Transgene Type: |
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Transgenic (Inducible, Recombinase) |
| Inducer: |
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tamoxifen |
| Mutation: |
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Insertion
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Tg(Tbx6-cre/ERT2)1Pa expression driven by
1 gene
Transgene expression driven by:
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Mutation details: Mouse BAC bmq-279H8 was modified to incorporate a cre/ERT2 with its own translational start site and polyA signal followed by an FRT-flanked kanamycin/neomycin cassette targeted to exon 1 of the Tbx6 gene. Flp-mediated recombination removed the FRT-flanked kan/neo cassette. Founder line 1Pa exhibited high levels of expression, and best recapitulated Tbx6 expression both temporally and spatially.
(J:244767)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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Tbx6
(mouse)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:244767 Concepcion D, et al., Cell lineage of timed cohorts of Tbx6-expressing cells in wild-type and Tbx6 mutant embryos. Biol Open. 2017 Jul 15;6(7):1065-1073 |
| All: |
1 reference(s) |
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Analysis Tools
