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Oxttm1.1(cre)Gcho
Targeted Allele Detail
Summary
Symbol: Oxttm1.1(cre)Gcho
Name: oxytocin; targeted mutation 1.1, Gloria B Choi
MGI ID: MGI:6113596
Synonyms: OxtCre
Gene: Oxt  Location: Chr2:130418093-130418974 bp, + strand  Genetic Position: Chr2, 63.24 cM
Alliance: Oxttm1.1(cre)Gcho page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:253430
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S/SvEv
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
Oxttm1.1(cre)Gcho expression driven by 1 gene
 
Mutation details: The targeting construct was generated to insert an IRES sequence, a Cre recombinase, and Frt-flanked PGK-neomycin resistance cassette at the 3' end of Oxt coding sequence by homologous recombination. Chimeric mice were bred to flp expressing mice to delete the neo selection cassette. (J:253430)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Oxt (mouse)
Summary of all recombinase alleles driven by Oxt.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Oxt Mutation:  20 strains or lines available
References
Original:  J:253430 Choe HK, et al., Oxytocin Mediates Entrainment of Sensory Stimuli to Social Cues of Opposing Valence. Neuron. 2015 Jul 1;87(1):152-63
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory