Tg(Mrc1-cre/ERT2)#Tobe
Transgene Detail
|
|
| Symbol: |
Tg(Mrc1-cre/ERT2)#Tobe |
| Name: |
transgene insertion, Kazuyuki Tobe |
| MGI ID: |
MGI:6113806 |
| Synonyms: |
CD206-CreERT2 |
| Transgene: |
Tg(Mrc1-cre/ERT2)#Tobe Location: unknown
|
| Alliance: |
Tg(Mrc1-cre/ERT2)#Tobe page
|
|
| Strain of Origin: |
Not Specified
|
|
| Transgene Type: |
|
Transgenic (Inducible, Recombinase) |
| Inducer: |
|
tamoxifen |
| Mutation: |
|
Insertion
|
| |
|
Tg(Mrc1-cre/ERT2)#Tobe expression driven by
1 gene
Transgene expression driven by:
| Organism |
Driver Gene |
Note |
| mouse |
Mrc1 (MGI:97142) |
|
|
| |
|
Mutation details: The 152 kb BAC clone (RP24-377D19) containing the exon coding translational start codon and upstream 133 kb sequence of mouse Mrc1 (CD206) gene was modified by introducing noncoding exon and intron from rabbit b-globulin gene, cre/ERT2, and rabbit b-globulin and simian virus 40 polyadenylation (pA) signal into the BAC. Line numbers were not indicated. The pound symbol (#) is used when no line is specified and/or lines are pooled.
(J:252768)
|
|
|
|
Activity: |
 Tissue activity of this recombinase allele
|
|
Driver:
|
Mrc1
(mouse)
|
| |
|
|
| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
|
|
| Original: |
J:252768 Nawaz A, et al., CD206+ M2-like macrophages regulate systemic glucose metabolism by inhibiting proliferation of adipocyte progenitors. Nat Commun. 2017 Aug 18;8(1):286 |
| All: |
2 reference(s) |
|
Analysis Tools
