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Jam2tm1.1(cre)Jrs
Targeted Allele Detail
Summary
Symbol: Jam2tm1.1(cre)Jrs
Name: junction adhesion molecule 2; targeted mutation 1.1, Joshua R Sanes
MGI ID: MGI:6116683
Synonyms: JAM-B Cre
Gene: Jam2  Location: Chr16:84571011-84622816 bp, + strand  Genetic Position: Chr16, 46.92 cM
Alliance: Jam2tm1.1(cre)Jrs page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:254378
Parent Cell Line:  E14TG2a (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout, Recombinase)
Mutations:    Insertion, Intragenic deletion
 
Jam2tm1.1(cre)Jrs expression driven by 1 gene
 
Mutation details: Exon 1 was replaced with Cre recombinase and an FRT-flanked SV40-neomycin cassette in reverse transcriptional orientation. Flp-mediated recombination removed the FRT-flanked neo cassette. (J:254378)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Jam2 (mouse)
Summary of all recombinase alleles driven by Jam2.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Jam2 Mutation:  121 strains or lines available
References
Original:  J:254378 Liu J, et al., Cellular and Molecular Analysis of Dendritic Morphogenesis in a Retinal Cell Type That Senses Color Contrast and Ventral Motion. J Neurosci. 2017 Dec 13;37(50):12247-12262
All:  3 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory